Chlamydia trachomatis : identi¢cationof susceptibilitymarkers for ocularand sexually transmitted infection by immunogenetics
نویسندگان
چکیده
The aim of this review is to present a concise overview of all data available on the immunogenetics of Chlamydia trachomatis infections, both sexually transmitted urogenital and ocular infections. Currently, candidate gene approaches are used to identify genes related to the susceptibility to and severity of C. trachomatis infections. The main focus in the review will be on data obtained by the study of human cohorts.
منابع مشابه
The Prevalence of Chlamydia trachomatis Infection in Women Attending Health Clinics in Shiraz, Islamic Republic of Iran
Background Chlamydia trachomatis (CT) is a common cause of sexually transmitted infections (STI) and a prevalent microorganism found in the vaginal discharge of sexually active women. The infection usually has no symptoms; although it may cause chronic complications such as pelvic inflammatory disease (PID), ectopic pregnancy, chronic pelvic pain, tubal infertility and cervical cancer. This stu...
متن کاملChlamydia trachomatis: identification of susceptibility markers for ocular and sexually transmitted infection by immunogenetics.
The aim of this review is to present a concise overview of all data available on the immunogenetics of Chlamydia trachomatis infections, both sexually transmitted urogenital and ocular infections. Currently, candidate gene approaches are used to identify genes related to the susceptibility to and severity of C. trachomatis infections. The main focus in the review will be on data obtained by the...
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Background Chlamydia trachomatis infections are the most prevalent sexually transmitted bacterial infections (STI) in the world that lead to a cause of tubal factor infertility in women. The aim of this study is to determine the presence of C.trachomatis by polymerase chain reaction (PCR) and ELISA. MaterialsAndMethods Endocervical swabs were collected from 80 women; 22 of them were asymptomati...
متن کاملردیابی کلامیدیا تراکوماتیس و مایکوپلاسما ژنیتالیوم در مایع منی مردان نابارور به روش Multiplex PCR
Background: Chlamydia trachomatis is the most common bacterial sexually transmitted infection in the world, but the effect of this infection on male fertility is still controversial. Despite reports of interaction between Mycoplasma genitalium and sperm, this pathogen in semen samples of infertile men is less studied. We studied, the prevalence of Chlamydia trachomatis and Mycoplasma genitalium...
متن کاملMultilocus sequence typing of urogenital Chlamydia trachomatis from patients with different degrees of clinical symptoms.
BACKGROUND In the past, contradictory results have been obtained linking Chlamydia trachomatis serovars (ompA gene) to different clinical courses of infection. METHODS A high resolution multilocus sequence typing (MLST) system was used to genotype 6 genetic regions, including ompA, in 70 Dutch urogenital C. trachomatis strains from patients with different degrees of defined clinical symptoms ...
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